To discern whether our blast model resulted in this type of etiopathogenic Tau modification, we probed brain tissues from blast-exposed rats with an antibody (AT8) that recognizes a hyperphosphorylated (Ser202, Thr205) Tau variant predisposed to form the paired helical filament (PHF) structures that comprise neurofibrillary tangles observed in CTE and related tauopathies [15]. Here, MAPT is linked to tauopathy.