Consistent with our speculation, Zwang and Yarden [27] observed that p38 mediated stress-induced endocytosis of EGFR augmented cytotoxicity produced by chemotherapeutic agents in HeLa cells, suggesting that stress-induced endocytosis of EGFR is important for down-regulating EGFR-mediated anti-apoptotic signaling in the cervical cancer cells. Here, EGFR is linked to cervical cancer.