To elucidate the relationship between FOXM1 and HSPA5 expression in colorectal cancer cells, we used two siRNAs against FOXM1 as well as FOXM1b or FOXM1c lentiviral high-expression vectors to transfect two colorectal cancer cell lines, namely SW1116 and LOVO cells. Here, HSPA5 is linked to colorectal cancer.