In contrast, the changes in lamin A/C and LAP2α distribution were also found in HeLa cells expressing GFP-Nup98-PMX1 or the non-HD fusion proteins GFP-Nup98-NSD1 and GFP-Nup98-NSD3 (S5A Fig), but were not seen in cells expressing other AML-related chromosomal translocation products, such as the AML1-ETO fusion protein (S5B Fig). The gene discussed is PRRX1; the disease is acute myeloid leukemia.