Messing et al. concluded that immediate adjuvant ADT after RP and PLND improved the survival of pN1 PCa patients, since 77% of patients who received immediate ADT were alive and had no evidence of recurrent disease, including undetectable serum PSA levels compared to 18% of patients who did not receive ADT after sugery[18]. The gene discussed is KLK3; the disease is posterior cortical atrophy.