To further evaluate the miR-124-1 inhibition of HCC cell growth and proliferation mediated by its target CASC3, we established stably overexpressing miR-124-1 MHCC-LM3 and Huh7 transfectants by infecting the cells with lentivirus encoding CASC3 (Figure 5B-a). Here, CASC3 is linked to hepatocellular carcinoma.