According to previous reports, lncRNAs: H19, HOTAIR (HOX transcript antisense intergenic RNA), HOTTIP (HOXA distal transcript antisense RNA), MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), PVT1 (plasmacytoma variant translocation 1) are most closely associated with PC. This evidence concerns the gene HOTTIP and pachyonychia congenita.