ARHGEF3 and neoplasm: In an effort to determine the potential downstream targets of ARHGEF3 that are involved in the promotion of NPC cell apoptosis, we compared mRNA expression profiles of siARHGEF3-CNE2 cells with those of control siNC-CNE2 cells using a Human Tumor Apoptosis RT2 ProfilerTM PCR Array containing 84 apoptosis-related genes.