CCL2 and posterior cortical atrophy: Numerous cytokines, such as transforming growth factors (TGFs) [23], fibroblast growth factors (FGFs) [24], interleukins (ILs) [25, 26], epithelial growth factor (EGF) [27], CCL2, CXCL12 [28, 29], etc., are involved in cancerous stromal-epithelial crosstalk and provide eligible microenvironment for PCa progression.