ABCG2 and carcinoma: It can be noted that 2,3,7,8-tetrachlorodibenso-p-dioxin (TCDD) treatment in the human intestinal C2bbe1 (a subclone of Caco2) cells as well as in other human secondary carcinoma cells of the colon, liver, and mammary glands resulted in induction of BCRP transcripts but failed in mouse-derived hepatic (hepa1c1c7), mammary (EMT 6), and intestinal (CMT93) cell lines [46].