In univariate Cox proportion hazard ratio analysis, age, tumor(T) stage, Node(N) stage, metastasis(M) stage, FOXD3, FOXO4 and FOXS1 expression were significantly associated with prognosis in terms of OS of patients with gastric cancer in the TCGA cohorts (p < 0.05, Table 2). This evidence concerns the gene FOXO4 and gastric cancer.