In the wild boar TB model, mycobacterial infections affect the expression of innate and adaptive immune response genes in mandibular lymph nodes and oropharyngeal tonsils, and Complement component 3 (C3) and Methylmalonyl-CoA mutase (MUT) have been proposed as correlates with resistance to natural mycobacterial infection [10, 14–16]. The gene discussed is C3; the disease is tuberculosis.