PLCB1 and cancer: PLC β1 was described to be selectively increased during myoblast and adipocyte differentiation (Faenza et al. 2004; O’Carroll et al. 2009), and evidences suggested that deletion of PLCB1 favours cancer progression in the myeloid lineage (Lo Vasco et al. 2004; Kaminskas et al. 2005).