INS and Insulin resistance: This is of special note as macrophage accumulation within the adipose tissue, especially visceral adipose tissue, is a consistent finding among insulin-resistant mice and humans and is thought to be a necessary component in diet-induced insulin resistance.1–3 Additionally, visceral adipose tissue-associated T cells are thought to be the major source of macrophage-recruiting chemokines.13 Our results indicated that the MCP1 and MCP3 levels were elevated in the absence of T cells, suggesting an alternative source for these chemokines.