FOLR1 and neoplasm: Greatly increased expression of pMP was found in tumor tissue of mice treated with F-LP/pMP compared with other groups, such as the LP/pMP group; and this might be due to the FRα-targeting properties of F-LP carriers, which would result in the induction of tumor cell apoptosis, inhibition of tumor cell proliferation, and tumor angiogenesis as detected by immunohistochemical staining.