ALOX5 and atherosclerosis: Human tissue studies as well as those using rodent models of atherosclerosis support a role for the LOX‐5 leukotriene pathway for inducing atherosclerosis.4, 6, 7, 24, 25, 26, 27 Corresponding case‐control studies in human subjects have reported positive associations between ALOX5 and atherosclerosis, though null findings have also been shown.