In another study, Satpathy, et al [24] reported that in an orthotopic human ovarian tumor xenograft model, HER-2- targeted magnetic NPs labeled with a near infrared dye (NIR-830) were specifically delivered into primary and disseminated ovarian tumors, enabling optical and MR imaging of tumors as small as 1 mm in the peritoneal cavity. This evidence concerns the gene ERBB2 and ovarian neoplasm.