Because tau phosphorylation at Ser262 was increased by Aβ42 [58] (Fig 5A), we asked whether stabilization of tau through tau phosphorylation at Ser262 and Ser356 contributed to the Aβ42-mediated increase in the level of tau phosphorylated at AD-related SP/TP sites, Ser202 and Thr231 [58] (Fig 2B). This evidence concerns the gene MAPT and Alzheimer disease.