ANGPT2 and Renal insufficiency: In particular, Ang-2 was a significant predictor of AKI (diagnosed based on the KDIGO criteria) and renal failure (diagnosed according to the modified Marshall scoring system) both in simple analysis (Table 3) and after adjustment for age, sex, and comorbidities, with ORs for AKI of 1.13 (1.01–1.26); 1.40 (1.11–1.77); and 1.66 (1.18–12.32) and ORs for renal failure of 1.14 (1.02–1.28); 1.38 (1.10–1.74); and 1.84 (1.16–2.92) per 1 ng/mL increase in Ang-2 concentration at 24, 48, and 72 hours, respectively.