Indeed, CB-LHRH’ was cytotoxic to ES-2 and NIH:OVCAR-3 (ovarian cancer cells) and HEC-1A (endometrial cancer cells) which express LHRHr, while displaying the weakest cytotoxicity in the LHRHr negative ovarian cancer cell line SKOV-3. This evidence concerns the gene GNRH1 and ovarian cancer.