FASLG and autoimmune polyendocrinopathy: The PROMISE Study (Predictors of pRegnancy Outcome: bioMarkers In APS and Systemic lupus Erythematosus) (clinicaltrials.gov#: NCT00198068), a prospective, multicenter observational study, aims to translate findings in mice to humans and evaluate the role of complement in lupus and aPL-associated pregnancy complications.