Here, we were interested in identifying a specificsurface marker expression pattern of both nephron stem/progenitors in hFK and cancerstem cells in WT, which could allow prospective isolation of the former as well asfurther characterization of the latter, towards more efficient eradication of the tumor.To achieve this goal, we investigated the expression of NCAM1, FZD7 and CD133 in thevarious cellular compartments of human fetal kidney (hFK), primary Wilms’tumor (pWT) and Wilms, tumor patient–derived xenografts (WT-PDX). Here, FZD7 is linked to neoplasm.