CASP7 and cancer: In addition, upregulation of p53 (53KDa) and Bax (23KDa), cleavage of Bid (22KDa) to its truncated form (15kDa) as well as cleavage of caspase-7 (20KDa), 8(43KDa), and 9(37KDa) were evident in both cancer cell lines (Fig. 12).