DMPK and Parkinson disease: For example, hsa-miR-1226-3p processed from an artificial conventional mirtron effectively silences aberrant myotonic dystrophy protein kinase [35], mmu-miR-1224 leucine-rich repeat serine/threonine-protein kinase 2, and α-synuclein Parkinson disease-associated genes [36], while an artificial 3′-tailed mirtron knocks down the expression of the vascular endothelial growth factor A [34].