In our study, 63 nonsyndromic SNHL patients with an identified molecular etiology were diagnosed with homozygous or compound heterozygous mutations in GJB2. All 63 of these patients presented prelingual SNHL and most of the patients (96.83%, 61/63) showed profound SNHL, and other 2 patients were severe hearing loss. The gene discussed is GJB2; the disease is hearing loss disorder.