Moreover, galectin-4 has also showed contradictory roles in cancer which may depend on the types of cancer (Rechreche et al., 1997; Belo et al., 2013; Maftouh et al., 2014; Cai et al., 2014; Hayashi et al., 2013; Hippo et al., 2001). This evidence concerns the gene LGALS4 and cancer.