The expression of S100B was decreased in BM of AML patients (median, 2.5×10−3; range, 7.6×10−5-9.1×10−2) compared with controls (median, 3.3×10−3; range, 1.1×10−3-1.8×10−2), however no statistical significance was found (Figure 4A–4D). Here, S100B is linked to acute myeloid leukemia.