NES and acute myeloid leukemia: Consistent with the immunohistochemical results, we demonstrated that the expression level of nestin was significantly lower in BM of AML patients (median, 8.7×10−5; range, 1.2×10−5-3.2×10−3) than that in controls (median, 3.1×10−4; range, 4.7×10−5-7.3×10−3; P=0.001).