rs1051730 is in this loci (beta between G allele and father's age at death=−0.0269, se=0.0049, p=3×10−8); the A allele of rs1051730 in the nicotinic acetylcholine receptor alpha 3 subunit CHRNA3 gene has been linked to smoking fewer cigarettes and lower risks of lung cancer, although this variant does not influence the chances of starting to smoke [21]. Here, CHRNA3 is linked to lung carcinoma.