Vassallo et al [35] revealed that the Wnt inhibitory factor 1 (WIF1), which was a secreted inhibitor of WNTs, suppressed the expression of MALAT1 in glioblastoma and loss of WIF1 enhanced the migratory potential of glioblastoma through Wnt5A that activated the Wnt/Ca2+ pathway and MALAT1. This evidence concerns the gene MALAT1 and glioblastoma.