POU5F1 and esophageal cancer: As expected, the mRNA level of β-catenin (P=0.0014, Figure 3A) and Lin28 (P=0.0026, Figure 3A) and the protein level of β-catenin (P=0.0311, Figure 3B), Lin28 (P=0.0178, Figure 3B) and OCT4 (P=0.0016, Figure 3B) were significantly decreased and E-cadherin mRNA (P=0.0011, Figure 3A) and protein (P=0.0037, Figure 3B) expression level were dramatically increased in si-MALAT1-treated esophageal cancer cells.