Patients with advanced CKD spontaneously reduce their mean protein and energy intake.19 For patients with CKD stages 3–5, strict protein control is advised to slow renal disease progression, decrease serum potassium and phosphate, and reverse metabolic acidosis.20 Upon dialysis initiation and stabilization, the general condition and nutritional status constantly improve.21 Almost several months after dialysis, the steady state and peak serum albumin level are achieved. The gene discussed is ALB; the disease is chronic kidney disease.