We can conclude that MUAC, TST, H/L, leptin, and adiponectin are correlated with the variant GG genotype of the LEPR 223 gene, whereas for TNF alpha and IL 8 are correlated with the AG genotype, protein serum level not being correlated with obesity, therefore being without importance in obesity determinism. The gene discussed is ADIPOQ; the disease is obesity due to melanocortin 4 receptor deficiency.