We can conclude that MUAC, TST, H/L, leptin, and adiponectin are correlated with the variant GG genotype of the LEPR 223 gene, whereas for TNF alpha and IL 8 are correlated with the AG genotype, protein serum level not being correlated with obesity, therefore being without importance in obesity determinism. This evidence concerns the gene TNF and obesity due to melanocortin 4 receptor deficiency.