When the baseline characteristics of patients who experienced an LRE were compared with those of patients who did not (Table 2), age (mean 54.3 vs. 43.0 years), proportion of hypertension (22.2 vs. 6.7%), histological F4 fibrosis stage (72.2 vs. 35.4%), and LS value (21.3 vs. 13.2 kPa) were significantly higher in patients with LRE development than in those without (all P <0.05), whereas ALT level (52.3 vs. 141 IU/L), HBV-DNA level (5.63 vs. 6.21 log10 IU/mL), and platelet count (129 vs. 142 109/L) were significantly lower in patients with LRE development (all P <0.05). Here, GPT is linked to Hypertension.