SNAI1 and cancer: Based on the roles of Snail in EMT and metastasis [37] and the poor prognostic outcomes of patients with high mRNA expression of Snail (Figure S2), we suggest that the increased Snail protein stability observed within 2 hours after treatment with TGFβ (Figure 3A), which increased the invasiveness of TD cells (Figure 3D and 3E), is important for the metastatic potential of mesenchymal cancer cells.