Based on the roles of Snail in EMT and metastasis [37] and the poor prognostic outcomes of patients with high mRNA expression of Snail (Figure S2), we suggest that the increased Snail protein stability observed within 2 hours after treatment with TGFβ (Figure 3A), which increased the invasiveness of TD cells (Figure 3D and 3E), is important for the metastatic potential of mesenchymal cancer cells. This evidence concerns the gene TGFB1 and cancer.