S4 Table shows that there are extensive changes in expression in all of the 60 HCMp genes during encystation, which was also seen in the 25 HCPs that are similar to HCMPs but with fewer cysteine-rich motifs (S4 Table). A few members of the Tenascin family (10 members in the WB strain) have been studied and they localized to the ESVs and the cyst wall [45]. We detected large gene expression changes in the Tenascin family in the early phase of encystation (S4 Table). The gene discussed is TNC; the disease is cyst.