In the time-to-persistent tTGA analyses, none of the SNPs reached this significance threshold, but 7 SNPs were identified in 5 novel celiac disease regions with p<10−4: rs117561283/IFNG (HR = 1.81; p = 2.1x10-5); rs8013918/FOS (HR = 0.80; p = 4.9x10-5); rs2409747/XKR6 (HR = 1.37; p = 5.4x10-5); rs114157400/BANK1 (HR = 1.62; p = 8.4x10-5); and rs72717025/FCGR2A (HR = 1.84; p = 9.6x10-5) (Fig 2A; Table 2). This evidence concerns the gene XKR6 and celiac disease.