CCND1 and cancer: Inhibition of Wnt/β-catenin signaling reduces c-Myc and cyclin D1 levels, thereby enhancing the radiosensitivity of cancer cells [24, 28, 29], but the precise regulatory relationships among β-catenin, c-Myc, cyclin D1, reactive oxygen species (ROS), and cell cycle arrest/progression require further clarification.