TARDBP and amyotrophic lateral sclerosis: Both familial and sporadic ALS have been linked to mutations in fused in sarcoma (FUS) (Kwiatkowski et al., 2009; Vance et al., 2009) (OMIM #608030) as well as in TAR DNA binding protein-43 kDa (TDP-43) (Kabashi et al., 2008; Sreedharan et al., 2008) (OMIM #612069).