However, a large number of genes located within the 1p36 region have been proposed as tumor suppressors in neuroblastoma and other tumors, including CHD5 [13], CAMTA1 [14, 15], miRNA-34a [16, 17], CASZ1 [18], KIF1B [19, 20], and the HES gene family [21]. The gene discussed is CASZ1; the disease is neuroblastoma.