Among those 55 GRFs, we found, for instance, HDAC2 involved in synaptic plasticity and neural circuits (Guan et al., 2009), ATF2 linked to neuronal apoptosis and cell migration (Yuan et al., 2009), and CHD2 implicated in ASD and epilepsy (Rauch et al., 2012; Table S3A). This evidence concerns the gene HDAC2 and epilepsy.