DDR2 and metastatic melanoma: Recently, Poudel and co-workers demonstrated that DDR2 was able to modulate MMP-2 and MMP-9 secretion in response to type I collagen and to regulate the invasive phenotype of murine metastatic melanoma cells through a regulation of ERK1/2 and NF-κB signaling pathways (Poudel et al., 2015).