Studies in A549 lung carcinoma cells showed that inhibiting the expression of DDR2 with siRNA is sufficient to alter activity of the NF-κB and the lymphoid enhancer-binding factor 1 (LEF-1) transcription factors and to inhibit EMT and cell migration induced by TGF-β1 (Walsh et al., 2011). Here, TGFB1 is linked to lung carcinoma.