Recently, polymorphisms in the juxtamembrane (R988C and T1010I) and sema (N375S) domains were detected in 1.7 and 4% of NSCLC patients, respectively, by PCR-based sequencing; however, no associations between MET mutations and clinical and pathological NSCLC features were observed [51, 52]. This evidence concerns the gene MET and non-small cell lung carcinoma.