MET and neoplasm: 4-point scoring system: 0 = no staining observed in invasive tumor cells; 1+ = weak, incomplete membrane staining in any proportion of the invasive tumor cells, or weak, complete circumferential membrane staining in fewer than 10% of cells; 2+ = weak but complete membrane staining in at least 10% of cells, or intense complete circumferential membrane staining in 30% or fewer of tumor cells; 3+ = intense complete ircumferential membrane staining in more than 30% of tumor cells. scores 0 and 1+ as c-MET low, and scores 2+ and 3+ as c-MET high