By contrast, although expression levels of OVA-IRES-GFP in the CD43-deficient MLL/AF9-OVA leukemia cells were comparable to, or even somewhat lower than, those in wild-type mice-derived leukemia cells (Fig 5D), CD43-deficient leukemia cells were killed by OVA-specific CTLs. This evidence concerns the gene SPN and leukemia.