By contrast, expression levels of R54 and B2 epitope were significantly higher on leukemia cells from wild-type recipients than those from Rag2-/- recipients (R54 MFI: 1.87 ± 0.13×104 vs. 1.29×104 ± 1.69×103, p<0.05; B2 MFI: 8.04 ± 0.78 ×103 vs. 3.45 ± 0.32×103, p<0.05) (Fig 6B and 6C). Here, RAG2 is linked to leukemia.