Accumulating evidence indicates that BRD7, as a tumor suppressor, has crucial roles in the progression of multiple cancers.40, 41 Here, we characterized the expression of BRD7 in NPC specimens and found that most NPC patients exhibit significant downregulation of the BRD7 protein, and low BRD7 protein levels were associated with poor prognosis of NPC patients. This evidence concerns the gene BRD7 and cancer.