Furthermore, we found that restoring the level of miR-141 in BRD7-overexpressing NPC cells can partially reverse the effect of BRD7 on cell proliferation and apoptosis in vitro and in vivo, indicating that the effect of BRD7 in NPC progression is partially dependent on its negative transcriptional regulation of miR-141. Here, BRD7 is linked to nasopharyngeal carcinoma.