MYC and nasopharyngeal carcinoma: Deregulation of miR-200 family members in cancers has been associated with the growth, apoptotic response and regulation of metastasis.23, 24, 25 However, numerous studies have yielded conflicting results regarding the role of miR-141 in tumor progression of different cancer types.26, 27, 28, 29 In our previous work, we have demonstrated that miR-141 was upregulated in NPC tissues and downregulated by the knockdown of c-Myc in NPC cells.30 Interestingly, as a direct target gene of c-Myc,31 BRD7 can also downregulate the expression of miR-141 in NPC cells.