INS and diabetes mellitus: 2007) and both induced and constitutive Dicer1 deletion in β‐cells results in impaired insulin secretion and diabetes (Kalis et al. 2011, Melkman‐Zehavi et al. 2011, Martinez‐Sanchez et al. 2015) with impaired glucose‐stimulated insulin secretion (GSIS) preceding changes in insulin content or β‐cell mass.