Specifically, a statistically significant ~50% decrease in the levels of MHC class II expression by CD11c+ cDC (Fig 4A), CD11c− cDC (Fig 4B), CD4+ MHC class II+ pDC (Fig 4C), and CD14+ monocytes (Fig 4D) was observed at 4 days post-infection, and thereafter recovered to baseline levels. Here, CD4 is linked to infection.