The primary outcome of this study was to evaluate the relationship between MPO levels, ROS production and leukocyte-endothelium interactions, adhesion molecules (E-Selectin, ICAM-1 and VCAM-1) and proinflammatory cytokines (IL-6 and TNF-α) in PCOS according to HOMA-IR. This evidence concerns the gene ICAM1 and polycystic ovary syndrome.