In addition, when these parameters were evaluated according to the presence or absence of IR, an increase in the adhesion molecule ICAM-1 was detected in PCOS non-IR patients (p<0.05, Fig 5D) and an increase in E-selectin (p<0.001, Fig 5B), ICAM-1 (p<0.01, Fig 5D) and VCAM-1 levels was observed in PCOS IR subjects (p<0.05, Fig 5F) with respect to controls. This evidence concerns the gene SELE and polycystic ovary syndrome.