The mean FHR-3 levels were significantly higher in the sepsis group (1.71-fold, p = 0.0173) compared to our healthy donor cohort (Fig 3C), but did not correlate with a classical marker for an acute phase reaction, i.e. CRP levels (rs = 0.208, p = 0.2166, Fig 3D). Here, CRP is linked to Sepsis.