DNER and cancer: From this perspective, the small cell-permeable thieno-triazolo-1, 4-diazepine, JQ1, which is a potent BET inhibitor, has recently been shown to exhibit anti-cancer effects in various cancer models such as NMC (NUT midline carcinoma) [37], hematopoietic malignancies [38] lung cancer [39], prostate cancer [40] and Osteosarcoma [31].