Furthermore, three loci which previously have been implicated in JIA and several other autoimmune diseases [10, 36, 37] – the PTPN22 locus on 1p13, the IL2RA locus on 10p15, and the ANTXR2 locus on 4q21.21 – were nominally associated with JIA (Additional file 1: Table S3). The gene discussed is PTPN22; the disease is juvenile idiopathic arthritis.