Potential oncogenes with high CNV gain also present in the top 20 most frequently mutated DNA repair genes (Table 1) include CDK12, PRKDC, CLK2, and EXO1, while potential tumor suppressors with high CNV loss found in Table 1 include TP53, ATM, TP53BP1, and WRN. This evidence concerns the gene TP53BP1 and neoplasm.